BDBM50026603 Buprenorphine::CHEBI:3216
SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]51CC[C@@]2(OC)[C@]([H])(C1)[C@](C)(O)C(C)(C)C)ccc3O
InChI Key InChIKey=RMRJXGBAOAMLHD-IHFGGWKQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50026603
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.0400nMAssay Description:Antagonist activity at kappa opioid receptor (unknown origin) assessed as stimulation of [35S]GTPgammaSMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.0670nMAssay Description:Displacement of [3H]-diprenorphine from human KOR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.620nMAssay Description:Displacement of [3H]U69593 form human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]U-69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Binding affinity to cloned human Opioid receptor kappa 1 transfected into hamster ovary cells using [3H]U-69593 as a radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]U69593 from human KOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]- U-69,593 radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.180nMAssay Description:Activity at human cloned kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Activity at human cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of U50488-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Partial agonist activity at human KOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillatio...More data for this Ligand-Target Pair